Critical Care Clinical Trials
Altering Sedation Paradigms to Improve Brain Injury and Survival in Severe
Sepsis (MENDS II)
Ventilated ICU patients frequently have sepsis and the majority have delirium.
The MENDS II study will determine the best sedative medication to reduce
delirium and improve survival and long-term brain function by comparing
propofol and dexmedetomidine in ventilated septic patients. Adult patients
with severe sepsis in the ICU that require sedation while on mechanical
ventilation may be eligible to participate.
Principal Investigators: Hollis O’Neal, MD
Status: Currently recruiting participants.
Click here for additional information about this clinical trial.